Set on a plateau almost 700 meters above sea level about 35 kilometers from Enna and a bit nearer Caltagirone, the city of Piazza Armerina is not without charm. Founded during the Norman era, its historical quarter has some beautiful churches, including a Baroque cathedral, as well as a well-preserved fortress (Spinelli Castle), but most visitors come here to see the Roman Villa, with its magnificent mosaics. Located a few kilometers outside town, the villa is one of the largest Roman dwellings of its kind to have survived antiquity, and probably belonged to a wealthy patrician. Depicting scenes from daily life, such as hunting, the mosaics are as remarkable for their sociological value as for their artistry. One of these, showing women clad in two-piece swimsuits exercising with barbells, could well describe a scene typical of the twentieth century. The "Villa del Casale" was built between 330 and 360 AD. The identity of its owner remains a subject of debate. However, three individuals are usually mentioned: Proculus Populonius, governor of Sicily from 314 to 337; Caeionus Rufus Volusianus, also called Lampadius, an influential and wealthy man; and Sabucinius Pinianus, probably of Roman birth. There are 3500 square meters of mosaics on the villa's floors, and some surviving wall paintings.

The city of Enna (known as Castrogiovanni until the 1920s) is located high on a mountaintop almost in the exact center of Sicily, affording a panoramic view overlooking the scenic valleys of Sicily's rugged interior. Enna's position makes it a natural strategic defensive position; any army that sought to control Sicily's interior would have to hold Enna.

Located off Route 288 near Aidone, in the province of Enna, Morgantina may have been settled by a certain King Morges who arrived with colonists from central Italy around 1300 BC. The early Morgetian culture was therefore somewhat distinct from the native Siculian civilisation. The Greeks absorbed the city some six centuries later. It was destroyed by the Romans during the Punic Wars in 211 BC, but eventually rebuilt as a Roman city. Eunus "liberated" Morgantina in 139 BC during the slave revolt, and died a prisoner in this city. Morgantina was abandoned around 30 BC (like Solunto) for unknown reasons. It had been a wealthy and prosperous city.

Once the location of a Saracen fortress, this high mountain town was rebuilt following the earthquake of 1693. This means that the architecture of its churches is typically Baroque, and while that may be considered unexceptional in Sicily, many older towns here do have at least some medieval elements. Caltagirone has a certain small town Sicilian charm, but it's most famous for its ceramic art. In fact, Sicilians refer to the "Caltagirone style" in ceramic pottery, characterized by ornate traditional motifs using a limited palette. Today, however, there's little difference between the style of Caltagirone and that of Santo Stefano di Camastra, Sicily's other traditional ceramics center. Being rather remote, Caltagirone is worth a stopover if you're passing through the area, but Santo Stefano is more conveniently situated off a main road between Palermo and Messina, and even has a beach.